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Intramyocardial transplantation of these IGF-1-overexpressing cardiac stem cells in the infarcted area also preserves stem cells in the damaged region and increases myocardial regeneration without affecting its differentiation into cardiomyocytes, smooth muscle, or endothelial cells (Jackson et al., 2015)

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The researchers reported that most patients received all medications in the delivered pathway, with the outlier being buprenorphine, which was provided in only around half of the cases